In Oracle RAC environments, Oracle recommends that you let the Oracle Agent manage the Oracle listeners for the databases.

• Use the lsnrctl executable located in the Grid home to administer Oracle Database 19c local and SCAN listeners.
  Do not attempt to use the lsnrctl executables from Oracle home locations for earlier releases, because they cannot be used with Oracle Database 19c.
• Use SRVCTL and the setenv command to modify the value of TNS_ADMIN for each listener.
  For listeners not managed by Oracle Clusterware, you can use a nondefault location for the listener.ora file by setting the TNS_ADMIN environment variable or registry value to point to the directory that contains the Oracle Net Services configuration files.